ПРИМЕНЕНИЕ ТИАЗОЛЬНЫХ ПРОИЗВОДНЫХ ДЛЯ ПОЛУЧЕНИЯ ЛЕКАРСТВЕННОГО СРЕДСТВА, ПРЕДНАЗНАЧЕННОГО ДЛЯ ЗАЩИТЫ МИТОХОНДРИЙ

摘要

The invention concerns compounds of general formula (I), wherein: A represents one of the radicals in which R⁵ represents independently a hydrogen atom, or alkyl; R⁶, R⁷ and R⁸ independently represent a hydrogen atom, alkyl, cycloalkyl, hydroxy or alkoxy; R¹¹ represents a hydrogen atom of alkyl; and R⁹, R¹⁰ and R¹² independently represent a hydrogen atom, alkyl, hydroxy or alkoxy; B represents a hydrogen atom or alkyl; n represents an integer from 0 to 5; R¹ and R² independently represent a hydrogen atom, alkyl or cycloalkyl; R³ and R⁴ independently represent a hydrogen atom or an alkyl radical, or R³ and R⁴ together form with the nitrogen atom which bears them a heterocycle optionally substituted comprising in all 1 to 2 heteroatoms and 5 to 7 members. Said compounds can be used for preparing a medicine for protecting mitochondria, and in particular a medicine for preventing or treating cirrhosis.