摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a treatment of diabetes mellitus, depending on effecting to differentiation of precursor cells of islet to matured insulin producing cells by stimulation of cooperativity of gastrin/cholecystokinin (CCK) receptor ligand, especially gastrin, and epidermal growth factor (EGF), especially transfer growth factorα(TGFα). <P>SOLUTION: The ex vivo method for differentiation of precursor cells to matured insulin secretion cells includes ex vivo stimulation of precursor cells of islet by using combination of gastrin/CCK receptor ligand peptide with EGF receptor ligand peptide. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p> |