发明名称 TREATMENT OF JUVENILE ONSET DIABETES
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a treatment of diabetes mellitus, depending on effecting to differentiation of precursor cells of islet to matured insulin producing cells by stimulation of cooperativity of gastrin/cholecystokinin (CCK) receptor ligand, especially gastrin, and epidermal growth factor (EGF), especially transfer growth factorα(TGFα). <P>SOLUTION: The ex vivo method for differentiation of precursor cells to matured insulin secretion cells includes ex vivo stimulation of precursor cells of islet by using combination of gastrin/CCK receptor ligand peptide with EGF receptor ligand peptide. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p>
申请公布号 JP2005087209(A) 申请公布日期 2005.04.07
申请号 JP20040234827 申请日期 2004.08.11
申请人 RTP PHARMA CORP;GENERAL HOSPITAL CORP 发明人 NARDI RONALD V;BRAND STEPHEN J
分类号 A61K38/00;A61K38/22;A61P3/10;C12N5/07;C12N5/074;(IPC1-7):C12N5/06 主分类号 A61K38/00
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