The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
申请公布号
WO2004112709(A3)
申请公布日期
2005.04.07
申请号
WO2004US19194
申请日期
2004.06.14
申请人
IRM LLC;LIU, HONG;TULLY, DAVID;ALPER, PHILLIP;EPPLE, ROBERT;CHATTERJEE, ARNAB;ROBERTS, MICHAEL
发明人
LIU, HONG;TULLY, DAVID;ALPER, PHILLIP;EPPLE, ROBERT;CHATTERJEE, ARNAB;ROBERTS, MICHAEL