发明名称 |
FACTOR VIII POLYPEPTIDE HAVING FACTOR VIII:C ACTIVITY |
摘要 |
Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.
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申请公布号 |
US2005074836(A1) |
申请公布日期 |
2005.04.07 |
申请号 |
US20010831679 |
申请日期 |
2001.05.10 |
申请人 |
BAXTER AKTIENGESELLSCHAFT |
发明人 |
LENTING PETRUS JOHANNES;VAN MOURIK JAN AART;MERTENS KOENRAAD;PANNEKOEK HANS;TURECEK PETER;SCHWARZ HANS-PETER;SCHEIFLINGER FRIEDRICH |
分类号 |
A61K38/00;A61K38/37;C07K14/705;C07K14/755;C12N15/12;(IPC1-7):C12P21/02;C12N5/06;C07H21/04;C07K14/775 |
主分类号 |
A61K38/00 |
代理机构 |
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