| 摘要 |
Administration of IL-21 results in decreasing autoimmune responses and there by provides a beneficial treatment for autoimmune diseases. Specific autoimmune diseases that may be treated include multiple sclerosis, rheumatoid arthriti s, systemic lupus erythematosus, psoriasis, ankylosing spondilitis, scleroderma , Type I diabetes, psoriatic arthritis, osteoarthritis, inflammatory bowel disease, atopic dermatitis and asthma. Pharmaceutical compositions can inclu de IL-21 polypeptides and active fragments thereof.
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