发明名称 Macrocyclic peptides active against the hepatitis C virus
摘要 Compounds of formula (I): wherein R<1 >is (C1-8)alkyl, (C3-7)cycloalkyl, {(C1-6)alkyl-(C3-7)cycloalkyl} or Het, which are all optionally substituted from 1 to 3 times with halo, cyano, nitro, O-(C1-6)alkyl, amido, amino or phenyl, or R<1 >is C6 or C10 aryl which is optionally substituted from 1 to 3 times with halo, cyano, nitro, (C1-6)alkyl, O-(C1-6)alkyl, amido, amino or phenyl; or a pharmaceutically acceptable salt thereof, useful as an inhibitor of the HCV NS3 protease.
申请公布号 US2005075279(A1) 申请公布日期 2005.04.07
申请号 US20030686755 申请日期 2003.10.16
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 LLINAS-BRUNET MONTSE;BAILEY MURRAY D.
分类号 A61K38/00;A61K38/12;C07K5/08;(IPC1-7):A61K38/12 主分类号 A61K38/00
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