Screening method of drug for treatment of neuropathic pain

摘要

The present invention relates to a screening method for a compound useful for treatment of neuropathic pain, and therapy for the treatment of neuropathic pain. The screening method comprises determining inhibitory activity on the action of P2X4 receptor or inhibitory activity on the activation of microglia, of test compounds. The pharmaceutical composition and the therapy employ a P2X4 receptor inhibitor or a microglial activation-inhibitor as active ingredient.