发明名称 |
METHODS AND MEANS FOR TREATING PROTEIN CONFORMATIONAL DISORDERS |
摘要 |
This invention relates to the recognition that autophagy plays a key role in the clearance of the intracellular protein aggregates which characterise Protein Conformational Disorders, such as Huntington's disease and Parkinson's disease. Methods and uses of autophagy inducing agents, such as rapamycin macrolides, in the treatment of Protein Conformational Disorders, are described herein. |
申请公布号 |
WO2004089369(A3) |
申请公布日期 |
2005.04.07 |
申请号 |
WO2004GB00690 |
申请日期 |
2004.02.24 |
申请人 |
CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED;RUBINSZTEIN, DAVID;RAVIKUMAR, BRINDA;WEBB, JULIE |
发明人 |
RUBINSZTEIN, DAVID;RAVIKUMAR, BRINDA;WEBB, JULIE |
分类号 |
A61K31/00;A61K31/436;A61P25/16;A61P25/28;A61P43/00;G01N33/50;G01N33/68 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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