METHOD AND KIT FOR ASSESSING THE RISK OF CARDIOVASCULAR PATHOLOGIES WITH ATHEROMATOUS ETIOLOGY
摘要
The invention relates to a molecolar method for in vitro assessment of the predisposition of a subject to develop cardiovascular pathologies, associated with rupture of an atherosclerotic plaque. The method is characterized by the identification of the -765G>C polymorphism in the COX-2 gone promotor, using genomic DNA sample(s) of the subject or a group of subjects. Moreover the invention relates to a kit for detection of such polymorphism.
申请公布号
WO2005014851(A3)
申请公布日期
2005.04.07
申请号
WO2004EP51711
申请日期
2004.08.04
申请人
GENE DESIGN & DEVELOPMENT S.R.L.;CIPOLLONE, FRANCESCO;MEZZETTI, ANDREA;MARTINOTTI, STEFANO