发明名称 |
Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor |
摘要 |
Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.
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申请公布号 |
US2005075348(A1) |
申请公布日期 |
2005.04.07 |
申请号 |
US20040983929 |
申请日期 |
2004.11.08 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
HARRIMAN GERALDINE C.B.;CARSON KENNETH G.;FLYNN DANIEL L.;SOLOMON MICHAEL E.;SONG YUNTAO;TRIVEDI BHARAT K.;ROTH BRUCE D.;KOLZ CHRISTINE N.;PHAM LY;SUN KUAI-LIN |
分类号 |
A61P31/18;C07D209/42;C07D235/26;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D487/04;C07D491/04;C07D491/08;(IPC1-7):A61K31/519;A61K31/53;A61K31/52 |
主分类号 |
A61P31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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