QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS

摘要

The invention concerns quinazoline derivatives of Formula (I), wherein each of R<1a>, R<1b>, R<2>, R<3> and a have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.