发明名称 |
PARTIALLY DOUBLE-STRANDED HAIRPIN OLIGONUCLEOTIDES IMMOBILIZABLE VIA THE LOOPED END AND COMPRISING A RESTRICTION SITE |
摘要 |
<p>This invention relates generally to nucleic acid hybridization and analysis. More specifically, oligonucleotide probes each containing both double and single-stranded regions and one looped end, or arrays of such oligonucleotide probes immobilized on a solid support via the looped end, are provided which are suitable for hybridization and analysis. Based on the molecular structure, specific methods for nucleic acid hybridization, processing, including automated processing, and analysis using the probes or array of probes immobilized on a solid surface, particularly including a reflective surface are also provided.</p> |
申请公布号 |
WO2005030987(A1) |
申请公布日期 |
2005.04.07 |
申请号 |
WO2003CA01536 |
申请日期 |
2003.10.03 |
申请人 |
ACCURATE BIOGENE SYSTEMS, INC.;VON SCHROEDER, HERBERT, PETER;BEARD, LARRY, A.;CHEN, XIANGHAI |
发明人 |
VON SCHROEDER, HERBERT, PETER;BEARD, LARRY, A.;CHEN, XIANGHAI |
分类号 |
B01J19/00;C07H21/04;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
B01J19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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