| 发明名称 |
SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)-PHTHALIMIDES AND -1-OXOISOINDOLINES AND METHOD OF REDUCING TNFA LEVELS |
| 摘要 |
<p>Substituted 2-(2,6-dioxopiperidin-3-yl)phthalimides and 1-oxo-2-(2,6- dioxopiperidin-3-yl)isoindolines reduce the levels of TNFalpha in a mammal. Typical embodiments are 1-oxo-2-(2,6-dioxo-3-methylpiperidin-3-yl) -4,5,6,7-tetrafluoroisoindoline and 1,3-dioxo-2-(2,6-dioxo-3- methylpiperidin-3-yl)-4-aminoisoindoline.</p> |
| 申请公布号 |
KR20050032629(A) |
申请公布日期 |
2005.04.07 |
| 申请号 |
KR20057004561 |
申请日期 |
2005.03.17 |
| 申请人 |
CELGENE CORP. |
发明人 |
CHEM, ROGER SHENGHU;MULLER, GEORGE W.;STIRLING, DAVID I. |
| 分类号 |
A61K31/4439;A61K31/445;A61K31/454;A61P1/00;A61P1/04;A61P7/00;A61P9/02;A61P9/04;A61P9/10;A61P17/06;A61P19/00;A61P19/02;A61P29/00;A61P31/06;A61P33/06;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07D401/04;(IPC1-7):A61K31/45 |
主分类号 |
A61K31/4439 |
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