发明名称 Indole, azaindole and related heterocyclic N-substituted piperazine derivatives
摘要 This invention provides compounds of Formula I, including pharmaceutically accceptable salts thereof, having drug and bio-affecting properties, their pharmaceutical compositions and method of use. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. The compounds of Formula I have the formula wherein: Z is Q is selected from the group consisting of m is 2; A is selected from the group consisting of cinnolinyl, napthyridinyl, quinoxalinyl, pyridinyl, pyrimidinyl, quinolinyl, isoquinolinyl, quinazolinyl, azabenzofuryl, and phthalazinyl each of which may be optionally substituted with one or two groups independently selected from methyl, methoxy, hydroxy, amino and halogen; and -W- is
申请公布号 US2005075364(A1) 申请公布日期 2005.04.07
申请号 US20040871931 申请日期 2004.06.18
申请人 发明人 YEUNG KAP-SUN;FARKAS MICHELLE;KADOW JOHN F.;MEANWELL NICHOLAS A.;TAYLOR MALCOLM;JOHNSTON DAVID;COULTER THOMAS STEPHEN;WRIGHT J. J. KIM
分类号 A61K31/405;A61K31/4745;A61K31/496;A61K31/497;A61K31/498;A61K31/502;A61K31/517;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D413/14;C07D471/02;C07D471/04;C07D487/04;C07D491/04;(IPC1-7):C07D471/02;A61K31/474 主分类号 A61K31/405
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