发明名称 |
Methods and targets of antibiotic resistance |
摘要 |
The present invention provides for a method of evolving and selecting cells resistant to a selective agent by inducing directed evolution in continuous culture while applying both a mutagenic and selective agent to the cells to determine the cells having resistance. This also provides a method of generating mutant drug targets useful for screening for effective compounds. The Figure is ageneralized schematic diagram of a chemostat of the present invention
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申请公布号 |
US6875582(B1) |
申请公布日期 |
2005.04.05 |
申请号 |
US20020069490 |
申请日期 |
2002.02.15 |
申请人 |
OMNISCIENCE PHARMACEUTICALS, INC. |
发明人 |
CHAPARIAN MICHAEL G.;AZAD ABUL |
分类号 |
C12Q1/18;G01N33/50;(IPC1-7):C12Q1/02;C12Q1/68;C12N15/00 |
主分类号 |
C12Q1/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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