MACROCYCLIC BETA-SECRETASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE
摘要
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the beta-secretase enzyme is involved.
申请公布号
WO2004062625(A3)
申请公布日期
2005.03.31
申请号
WO2004US00085
申请日期
2004.01.02
申请人
MERCK & CO., INC.;COBURN, CRAIG, A.;STACHEL, SHAWN, J.;VACCA, JOSEPH, P.
发明人
COBURN, CRAIG, A.;STACHEL, SHAWN, J.;VACCA, JOSEPH, P.