发明名称 |
Immunotherapeutic combinations for the treatment of tumours that overexpress gangliosides |
摘要 |
The present invention is related to the field of immunology and more specifically with immunotherapeutic combinations used for controlling growth and/or cell proliferation of tumors. By means of the present invention a therapeutic effect against tumors is observed by the combination of idiotypic vaccines whose principle active is an anti-ganglioside antibody (Ab1), with idiotypic vaccines whose principle active is anti-idiotype antibody (Ab2) obtained against an anti-ganglioside antibody, or vaccines whose principle active is one or more gangliosides. Combinations of these vaccines are described that cause a synergic therapeutic effect against tumors. The referred combinations can be applied to patients in different clinical conditions of tumors that express gangliósidos.
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申请公布号 |
US2005069535(A1) |
申请公布日期 |
2005.03.31 |
申请号 |
US20040473978 |
申请日期 |
2004.10.25 |
申请人 |
FERNANDEZ MOLINA LUIS ENRIQUE;VAZQUEZ LOPEZ ANA MARIA;PEREZ RODRIGUEZ ROLANDO;CARR PEREZ ADRIANA;DIAZ RODRIGUEZ YILDIAN;ALFONSO FERNANDEZ MAURO A. |
发明人 |
FERNANDEZ MOLINA LUIS ENRIQUE;VAZQUEZ LOPEZ ANA MARIA;PEREZ RODRIGUEZ ROLANDO;CARR PEREZ ADRIANA;DIAZ RODRIGUEZ YILDIAN;ALFONSO FERNANDEZ MAURO A. |
分类号 |
C12N15/09;A61K31/7032;A61K31/739;A61K39/00;A61K39/395;A61P35/00;A61P35/04;A61P37/00;A61P37/04;A61P43/00;C07K16/00;C07K16/18;C07K16/30;C07K16/42;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/20;C12P21/08;(IPC1-7):A61K39/395 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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