METHOD FOR PREPARING THERMOFORMED COMPOSITIONS CONTAINING ACRYLIC POLYMER BINDERS, PHARMACEUTUAL DOSAGE FORMS AND METHODS OF PREPARING THE SAME
摘要
Thermoformed or hot melt extruded pharmaceutical compositions containing an active pharmaceutical ingredient, acrylic enteric polymer and plasticizer are disclosed. Methods of making the same as well as various pharmaceutical dosage forms are also disclosed. In preferred aspects, a thermoformable mixture is in a powder form and includes an active ingredient, plasticizer, acrylic polymer and optional excipients which enhance the performance of the extrudate after being incorporated into a dosage form.
申请公布号
WO2004100883(A3)
申请公布日期
2005.03.31
申请号
WO2004US14109
申请日期
2004.05.06
申请人
BPSI HOLDINGS, INC.;BOARD OF REGENTS;FARRELL, THOMAS, P.;FEGELY, KURT, A.;YOUNG, CHRISTOPHER, R.;CROWLEY, MICHAEL;MCGINITY, JAMES, W.
发明人
FARRELL, THOMAS, P.;FEGELY, KURT, A.;YOUNG, CHRISTOPHER, R.;CROWLEY, MICHAEL;MCGINITY, JAMES, W.