This invention relates to a method for the evaluation of potential therapeutic agents for the treatment of incontinence, as well as to a method for discovering new therapeutic agents for the treatment of incontinence.The method is based on instilling cold liquid into the bladder of a guinea pig in the presence or absence of a test compound, and measuring the lowering of the threshold volume for bladder contractions compared to the normal cystometric capacity.
申请公布号
WO2005004883(A3)
申请公布日期
2005.03.31
申请号
WO2004IB02275
申请日期
2004.07.05
申请人
PFIZER LIMITED;GARDINER, JENNIFER, CHRISTINE;ZANZINGER, JOHANNES, FRIEDRICH;PFIZER, INC.
发明人
GARDINER, JENNIFER, CHRISTINE;ZANZINGER, JOHANNES, FRIEDRICH