发明名称 |
NOVEL STABLE CRYSTAL FORM OF N-TRANS-4-ISOPROPYLCYCLOHEXYL CARBONYL)-D-PHENYLALANINE AND PROCESS OF PREPARATION |
摘要 |
<p>This invention relates to novel stable crystal form of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine may be produced by crystallisation of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine with a solvent at 25 - 38 DEG C and forming crystals in the solvent. The crystal form may be formed by recrystallisation out of solution. The Crystal form obtained in this way have different melting point, infra red spectrum and X-ray diffraction patterns from previously known forms "B-type" and "H-Type" of the compound.</p> |
申请公布号 |
EP1435912(A4) |
申请公布日期 |
2005.03.30 |
申请号 |
EP20010978760 |
申请日期 |
2001.11.05 |
申请人 |
ALEMBIC LIMITED |
发明人 |
SHAH, VRAJESH;HITKARI, ANURAG;DEO, KESHAV;RENGARAJU, SRINIVASAN |
分类号 |
C07C233/63;(IPC1-7):A61K9/14;C07C229/00;A61K9/16 |
主分类号 |
C07C233/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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