发明名称 Process for preparation of tertiary alcohol esters
摘要 The production process of the present invention comprises a step of allowing a carboxylic acid derivative represented by the formula (1):wherein ring Z is a monocyclic or polycyclic non-aromatic or aromatic ring, and R<1 >is a halogen atom or a group represented by the formula (2):wherein R is a hydrogen atom or a hydrocarbon group, to react with an organometallic compound represented by the formula (3):wherein R<2 >is a hydrocarbon group, and M is a metallic atom which may have a ligand, or the formula (4):wherein Y is a halogen atom,and a carboxylic acid halide represented by the formula (5):wherein R<3 >is a hydrocarbon group or a heterocyclic group, and X is a halogen atom,to yield the tertiary alcohol ester represented by the formula (6):wherein Z, R<2 >and R<3 >have the same meanings as defined above.According to the present invention, a tertiary alcohol compound having a tertiary carbon combined with a ring group can be easily and efficiently produced from carboxylic acid derivative which is comparatively cheap and readily available.
申请公布号 US6872846(B2) 申请公布日期 2005.03.29
申请号 US20030399516 申请日期 2003.04.17
申请人 DAICEL CHEMICAL INDUSTRIES, LTD. 发明人 NAGANO SHINYA;SHIMOJITOSHO HIROSHI
分类号 C07C67/08;C07B49/00;C07C33/05;C07C45/68;C07C67/14;C07C69/03;C07C69/54;(IPC1-7):C07C69/74 主分类号 C07C67/08
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