СПОСОБЫ ДЕТЕКЦИИ КЛЕТОК С АНОМАЛИЯМИ В ЧИСЛЕ ХРОМОСОМ

摘要

The invention provides methods for detecting mitotic cells having numerical chromosomal abnormalities and agents inducing numericalchromosomal abnormalities in cells. In a preferred embodiment, the method comprises staining a cell with a mitotic marker: that detects cells in mitosis, and a quantitative DNA stain, indicating the amount of DNA in the mitotic cell. Stained cells are preferably analyzed by flow cytometry.