| 发明名称 |
СОЕДИНЕНИЯ, ВОЗДЕЙСТВУЮЩИЕ НА ГЛЮКОКИНАЗУ |
| 摘要 |
The invention relates to compounds of Formula (IIf) or a salt or solvate thereof, wherein R<3>, Het, X and Z<1> are as described in the specification, pharmaceutical compositions containing them, their use in the preparation of a medicament for the treatment or prevention of a disease condition mediated through glucokinase (GLK), such as type 2 diabetes, and methods for their preparation. <CHEM> |
| 申请公布号 |
RU2004104333(A) |
申请公布日期 |
2005.03.27 |
| 申请号 |
RU20040104333 |
申请日期 |
2002.08.15 |
| 申请人 |
АстраЗенека АБ (SE) |
发明人 |
БОЙД Скотт (GB);КОЛКЕТТ Питер Уиль м Родни (GB);ХАРГРИВЗ Родни Брайан (GB);БАУКЕР Сьюзан Саксон (GB);ДЖЕЙМС Роджер (GB);ДЖОНСТОН Крейг (GB);ДЖОУНЗ Клиффорд Дейвид (GB);МАККЕРРЕЧЕР Даррен (GB);БЛОК Майкл Хауард (GB) |
| 分类号 |
A61K31/165;A61K31/167;A61K31/192;A61K31/195;A61K31/341;A61K31/415;A61K31/4155;A61K31/42;A61K31/425;A61K31/426;A61K31/427;A61K31/428;A61K31/433;A61K31/44;A61K31/4402;A61K31/4436;A61K31/4439;A61K31/444;A61K31/445;A61K31/454;A61K31/455;A61K31/496;A61K31/4965;A61K31/497;A61K31/50;A61K31/501;A61K31/505;A61K31/506;A61K31/5377;A61P3/04;A61P3/06;A61P3/10;A61P43/00;C07D213/75;C07D213/76;C07D213/82;C07D213/85;C07D231/40;C07D233/48;C07D237/20;C07D237/24;C07D239/42;C07D239/47;C07D241/20;C07D241/26;C07D241/28;C07D261/14;C07D277/20;C07D277/46;C07D277/54;C07D277/56;C07D277/58;C07D277/82;C07D285/12;C07D285/135;C07D307/66;C07D307/68;C07D401/04;C07D403/04;C07D405/12;C07D409/12;C07D409/14;C07D413/04;C07D413/12;C07D413/14;C07D417/04;C07D417/12;C07D417/14 |
主分类号 |
A61K31/165 |
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