ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ВКЛЮЧАЮЩАЯ АГОНИСТ A1/A2-АДЕНОЗИНОВЫХ РЕЦЕПТОРОВ И ИНГИБИТОР ОБМЕНА НАТРИЙ-ВОДОРОДНЫХ ИОНОВ

摘要

The invention is directed to pharmaceutical composition comprising a compound having adenosine A1/A2 agonistic activity, a sodium-hydrogen exchanger inhibitory compound and a pharmaceutically acceptable carrier. The invention is also directed to a method cardioprotection in a patient in need thereof comprising administering to said patient pharmaceutically effective amounts of a compound having adenosine A1/A2 agonistic activity and a sodium-hydrogen exchanger inhibitory compound. This invention is also directed to the use of pharmaceutically effective amounts of a compound having adenosine A1/A2 agonistic activity and a sodium-hydrogen exchanger inhibitory compound in the preparation of a medicament for providing cardioprotection to a patient in need thereof. This invention is also directed to a kit for providing cardioprotection in a patient in need thereof, said kit comprising a plurality of separate containers, wherein at least one of said containers contains a compound having adenosine A1/A2 agonistic activity and at least another of said containers contains a sodium-hydrogen exchanger inhibitory compound, and said containers optionally contain a pharmaceutical carrier.