发明名称 METHOD FOR INHIBITING PRION PROTEIN AND USE OF THE METHOD
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for inhibiting abnormal-type prion protein applicable to preventing and treating prion disease for which no effective therapy has been established yet at present, and to provide a method for using the method. <P>SOLUTION: The method for inhibiting the accumulation of the abnormal-type prion protein comprises inhibiting the expression of a normal-type prion protein using siRNA in prion-infected cells. This method is applicable to preventing and treating prion disease. <P>COPYRIGHT: (C)2005,JPO&NCIPI
申请公布号 JP2005073573(A) 申请公布日期 2005.03.24
申请号 JP20030307666 申请日期 2003.08.29
申请人 NAGASAKI UNIV 发明人 SAKAGUCHI SUEHIRO;TAHIRA KAZUMASA
分类号 C12N15/09;A01K67/027;A61K31/7105;A61K38/00;A61K45/00;A61K48/00;A61P25/28;A61P43/00;C12N15/113 主分类号 C12N15/09
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