发明名称 |
METHOD FOR INHIBITING PRION PROTEIN AND USE OF THE METHOD |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for inhibiting abnormal-type prion protein applicable to preventing and treating prion disease for which no effective therapy has been established yet at present, and to provide a method for using the method. <P>SOLUTION: The method for inhibiting the accumulation of the abnormal-type prion protein comprises inhibiting the expression of a normal-type prion protein using siRNA in prion-infected cells. This method is applicable to preventing and treating prion disease. <P>COPYRIGHT: (C)2005,JPO&NCIPI |
申请公布号 |
JP2005073573(A) |
申请公布日期 |
2005.03.24 |
申请号 |
JP20030307666 |
申请日期 |
2003.08.29 |
申请人 |
NAGASAKI UNIV |
发明人 |
SAKAGUCHI SUEHIRO;TAHIRA KAZUMASA |
分类号 |
C12N15/09;A01K67/027;A61K31/7105;A61K38/00;A61K45/00;A61K48/00;A61P25/28;A61P43/00;C12N15/113 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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