METHODS AND COMPOSITIONS FOR THE TREATMENT OF PARKINSON'S DISEASE AND OTHER alpha-SYNUCLEINOPATHIES
摘要
The present invention provides novel methods for the treatment of Parkinson's disease and other alpha-synucleinopathies. The methods of the invention include treatment with inhibitors of transglutaminase, which can inhibit aggregation of alpha-synuclein. Also provided are screening assays for novel inhibitors of transglutaminase which may be used in the treatment of Parkinson's disease and other alpha-synucleinopathies.
申请公布号
WO2004069175(A3)
申请公布日期
2005.03.24
申请号
WO2004US02724
申请日期
2004.01.30
申请人
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;MOURADIAN, M., MARAL;JUNN, EUNSUNG
