发明名称 |
FORMULATIONS OF ANTHRAQUINONE DERIVATIVES |
摘要 |
A stable, sterile aqueous solution of a compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R'R" of at least 2 carbon atoms and R' and R" are each separately selected from C1-4 alkyl grou ps and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups, or R' and R" together are a C2-6 alkylene group, is formulated in a unit dosage form in a sealed container, said solution having a concentration of the compound of formula ( I) up to 150 mg/ml and a pH in the range of 5 to 9. The solution may be prepare d without a freeze drying step.
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申请公布号 |
CA2534485(A1) |
申请公布日期 |
2005.03.24 |
申请号 |
CA20042534485 |
申请日期 |
2004.09.16 |
申请人 |
BTG INTERNATIONAL LIMITED |
发明人 |
ELLIOTT, MOIRA ALEXANDRA;HALBERT, GAVIN WILLIAM;FORD, STEVEN JOHN |
分类号 |
A61K9/08;A61K47/02;C07C225/30 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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地址 |
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