发明名称 |
Aryl or heteroaryl amide compounds |
摘要 |
This invention provides a compound of the formula (I): wherein A represents a phenyl group or the like: B represents an aryl or the like: E represents a 1,4-phenylene group; R<1 >and R<2 >independently represent a hydrogen atom or the like: R<3 >and R<4 >independently represent a hydrogen atom or the like: R<5 >represents -CO2H or the like: R<6 >represents an alkyl group having from 1 to 6 carbon atoms or the like: X represents a methylene group or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.
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申请公布号 |
US2005065188(A1) |
申请公布日期 |
2005.03.24 |
申请号 |
US20040932463 |
申请日期 |
2004.09.02 |
申请人 |
NAKAO KAZUNARI;NUKUI SEIJI;OKUMURA YOSHIYUKI;YAMAGISHI TATSUYA |
发明人 |
NAKAO KAZUNARI;NUKUI SEIJI;OKUMURA YOSHIYUKI;YAMAGISHI TATSUYA |
分类号 |
A61P29/00;C07C233/87;C07C235/60;C07C255/57;C07D213/64;C07D213/643;C07D213/65;C07D213/82;C07D257/04;C07D401/12;C07D417/12;(IPC1-7):A61K31/443;A61K31/355;A61K31/198;A61K31/195;A61K31/18 |
主分类号 |
A61P29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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