APPARATUS AND METHOD FOR IDENTIFYING THERAPEUTIC TARGETS USING A COMPUTER MODEL
摘要
Apparatus and method for identifying therapeutic targets of a biological system in a disease state are described. In one implementation, a method uses a computer model of the biological system. The method includes identifying a set of functions of a biological constituent of the biological system. The method also includes executing the computer model in the absence of a modification of the set of functions to produce a first output and executing the computer model based on the modification of the set of functions to produce a second output. The method further includes comparing the second output with the first output to identify the biological constituent as a therapeutic target.
申请公布号
WO2005026911(A2)
申请公布日期
2005.03.24
申请号
WO2004US29639
申请日期
2004.09.10
申请人
ENTELOS, INC.;PATERSON, THOMAS, S.;WENNERBERG, LEIF, GUSTAF