POLYSULFONE BASED SELECTIVE PERMEATION HOLLOW FIBER MEMBRANE AND METHOD FOR PRODUCTION THEREOF

摘要

[PROBLEM] To provide a hollow fiber type blood purifier having a hydrophobic polymer and a hydrophilic polymer, which is reduced in the amount of a material eluted from a membrane, is excellent in safety, is reduced in the instability of performance due to the contact with blood and is excellent in the compatibility with blood. [MEANS FOR SOLVING PROBLEMS] A hollow fiber membrane exhibiting high uniformity of membrane structure and holes in an inner surface, having good balance of hydrophilic and hydrophobic properties, being reduced in the amount of a material eluted from the membrane, and being excellent in the compatibility with blood can be produced, in the case that the optimum polymer composition is selected for a spinning fluid containing a hydrophobic polymer and a hydrophilic polymer dissolved therein, the relationship that the linear velocity for the discharge of a hollow forming agent > the linear velocity for the discharge of a spinning fluid is satisfied when the spinning fluid is discharged from a nozzle together with the hollow forming agent and introduced into a coagulation bath via a space section, and a hollow fiber membrane is coagulated while being stretched in the coagulation bath.