发明名称 |
ANTISENSE OLIGONUCLEOTIDES FOR PREVENTION OF METASTASIS FORMATION OF CANCER CELLS |
摘要 |
<p>Described are antisense oligonucleotides targeted to the gene encoding osteopontin, bone sialoprotein II and/or osteonectin, wherein said oligonucleotides inhibit the expression of said gene(s). Moreover, the therapeutic use of said antisense oligonucleotides is described, e.g., for the treatment or prevention of cancer/metastasis, preferably osteolytic metastasis or metastasis of breast cancer cells.</p> |
申请公布号 |
WO2005026357(A1) |
申请公布日期 |
2005.03.24 |
申请号 |
WO2004EP09738 |
申请日期 |
2004.09.01 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM;IMMUNDIAGNOSTIK AG;ADWAN, HASSAN;BERGER, MARTIN;BAEUERLE, TOBIAS;ARMBRUSTER, FRANZ |
发明人 |
ADWAN, HASSAN;BERGER, MARTIN;BAEUERLE, TOBIAS;ARMBRUSTER, FRANZ |
分类号 |
A61K31/711;A61K38/00;A61P35/00;A61P35/04;C07H21/00;C12N15/113;(IPC1-7):C12N15/11;A61K31/00 |
主分类号 |
A61K31/711 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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