发明名称 |
SOLUBLE ECTODOMAIN FRAGMENTS OF MET AND USES THEREOF |
摘要 |
<p>The invention relates a fragment derived from the MET ectodomain which the inventors have found is capable, in monomer form, of binding to HGF/SF either in the presence or absence of heparin. The availability of soluble, monomeric forms of the MET receptor enabled studies of its solution properties and HGF/SF binding and provides an assay comprising the steps of (a) providing a MET ectodomain fragment; (b) providing an agent; and (c) determining the extent to which the agent interacts with said fragment.</p> |
申请公布号 |
WO2005026361(A1) |
申请公布日期 |
2005.03.24 |
申请号 |
WO2004GB03957 |
申请日期 |
2004.09.15 |
申请人 |
MEDICAL RESEARCH COUNCIL;GHERARDI, ERMANNO |
发明人 |
GHERARDI, ERMANNO |
分类号 |
A61K38/00;C07K14/71;C12N15/12;(IPC1-7):C12N15/12;A61K38/17;G01N33/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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