发明名称 |
Oral transmucosal methadone |
摘要 |
Pharmaceutical compositions for oral-transmucosally administering methadone. For oral transmucosal delivery, the compositions comprise an oral dissolution agent and methadone in a dosage formulation. The dissolution agent generally causes the formulation to break down or dissolve in the oral cavity. The formulation is buffered to a pH of at least 6 for substantial absorption of the methadone through the oral mucosal tissue from the dissolved dosage form.
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申请公布号 |
US2005065175(A1) |
申请公布日期 |
2005.03.24 |
申请号 |
US20030669490 |
申请日期 |
2003.09.24 |
申请人 |
XANODYNE PHARMACAL, INC. |
发明人 |
GONZALES GILBERT R.;MANFREDI PAOLO L. |
分类号 |
A61K9/00;A61K31/485;(IPC1-7):A61K31/485;A61K9/14;A61K9/68 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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