发明名称 AN AGENT FOR PLASMINOGEN-ACTIVATION AND MATRIX METALLOPROTEINASE ASSOCIATED CONDITIONS AND METHODS OF USE
摘要 <p>The present invention provides methods and compounds useful in the treatment of conditions such as metastatic cancer spread and atherosclerosis using oxamflatin and derivatives thereof. It has been found that oxamflatin and derivatives thereof are able to modulate the plasminogen-activation/matrix metalloproteinase system leading to the ability to control degradation of extracellular matrix proteins.</p>
申请公布号 WO2005025557(A1) 申请公布日期 2005.03.24
申请号 WO2004AU01259 申请日期 2004.09.16
申请人 MONASH UNIVERSITY;DEAR, ANTHONY, EDWIN;MEDCALF, ROBERT, LINDSAY 发明人 DEAR, ANTHONY, EDWIN;MEDCALF, ROBERT, LINDSAY
分类号 C07C323/60;A61K31/165;A61K31/18;A61P35/00;C07C311/08;C07C311/21;C07C323/61;C07C333/12;C07D209/40;C07D309/32;(IPC1-7):A61K31/18;C07C311/15;C07C311/31;C07C311/17 主分类号 C07C323/60
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