发明名称 |
Drug activation process and vibrational mill therefor |
摘要 |
The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterised by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.
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申请公布号 |
NZ530825(A) |
申请公布日期 |
2005.03.24 |
申请号 |
NZ20020530825 |
申请日期 |
2002.06.03 |
申请人 |
EURAND PHARMACEUTICALS LTD |
发明人 |
DOBETTI, LUCA;RABAGLIA, LEONARDO;BRESCIANI, MASSIMO |
分类号 |
A61K9/14;B02C17/14;B02C17/24;(IPC1-7):B02C17/14 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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