发明名称 |
MODULATION OF GENE EXPRESSION USING DNA-RNA HYBRIDS |
摘要 |
The present invention is directed to novel DNA-RNA hybrids comprising either a DNA sense strand and an RNA antisense strand, or an RNA sense strand and a DNA antisense strand. The compounds of the invention, and compositions and arrays comprising the same, may be used for a variety of purposes, including inhibiting gene expression, treating disease and infection, determining the function of genes, and identifying and validating novel drugs and their targets. |
申请公布号 |
WO2004078941(A3) |
申请公布日期 |
2005.03.24 |
申请号 |
WO2004US06666 |
申请日期 |
2004.03.04 |
申请人 |
OLIGO ENGINE, INC.;HAUSER, TODD;LOOMIS, AARON;HENSEL, DAVID |
发明人 |
HAUSER, TODD;LOOMIS, AARON;HENSEL, DAVID |
分类号 |
A61K31/675;A61K38/00;C07H21/02;C12N15/11;C12Q1/68 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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