PROCESS FOR THE SYNTHESIS OF 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXYNAPHTHONITRILE

摘要

A process for making a compound of formula I wherein R1, is CN, F or CI; R2 is H or Br; and R3 and R4 are each independently H or F. These compounds are useful in the treatment of chronic inflammatory diseases, such as rheumatoid arthritis.