| 摘要 |
<p>Methods and compositions for use in blocking or inhibiting the activity(s) o f WISP-1 polypeptide on chondrocytes are provided. WISP-1 antagonists include anti-WISP-1 antibodies, WISP-1 immunoadhesins and WISP-1 variants (and fusio n proteins thereof) which inhibit or neutralize the effects of WISP-1 on mammalian chondrocytes.</p> |
