Immunogenic constructs for inducing antiviral neutralizing antibodies in humans and animals, comprises selected amino acid sequences from specified locations of envelope proteins

摘要

An immunogenic construct for inducing antiviral neutralizing antibodies in humans and animals, comprising selected amino acid sequences from specified locations of envelope proteins, is new : An immunogenic construct for inducing antiviral neutralizing antibodies in humans and animals, comprising selected amino acid sequences from specified locations of envelope proteins. The amino acid sequences are selected from: (a) a first region of the envelope proteins located between the membrane passage and a first alpha-helical structure; (b) from a second region located between the fusion domain and a second alpha-helical structure; and/or (c) the construct which comprises of the respective amino acid sequence coding DNA. Independent claims are included for the method of inducing an antibody response, a corresponding pharmaceutical agent, amino acid sequence, neutralizing antibody, kit detecting antibodies, virus antigens and immuno assay.