| 摘要 |
<p>The present invention relates to compositions comprising terpenlactone compounds and, more particularly, to compositions comprising Gincolide A, Gincolide B and bilobalide as an effective ingredients. Compared with ketoconazole, used as a dandruff treatment agent, the composition comprising ginkgolide A, ginkgolide B and bilobalide according to the present invention has excellent inhibitory activity against Pityrosporum ovale, causative of dandruff in humans and has superior curative effects on dandruff and scalp itching and preventive effect on depilation. Also, the composition of the present invention effectively inhibits the activity of Malassezia pachydermatis, causative of dandruff in dogs, and shows good deodorizing effects in animals, without side effects such as skin erythema. Thus, the composition of the present invention is suitable for use in shampoo for dandruff treatment and depilation prevention as well as in animal shampoo. Furthermore, the composition comprising ginkgolide A, ginkgolide B and bilobalide according to the present invention can be used in antibacterial and antifungal agents, pesticides and insect repellents thanks to its high activity against bacteria, fungi, pests and insects.</p> |
