Peptides are provided that inhibit the interaction of an IGF with any one of its binding proteins and not to a human IGF receptor. These IGF agonist peptides are useful to increase serum and tissue levels of active IGFs in a mammal.
申请公布号
WO0078801(A9)
申请公布日期
2005.03.24
申请号
WO2000US17023
申请日期
2000.06.19
申请人
GENENTECH, INC.
发明人
CHEN, YVONNE, MAN-YEE;COCHRAN, ANDREA, G.;LOWMAN, HENRY, B.;SKELTON, NICHOLAS, J.