发明名称 |
Acyl CoA:cholesterol acyltransferase (ACAT-2) |
摘要 |
Nucleic acid compositions encoding novel ACAT proteins, as well as the novel ACAT-2 proteins, (ACAT-2) are provided. Also provided are methods of producing the subject nucleic acid and protein compositions. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including diagnostic and therapeutic agent screening applications, as well as in treatment therapies for disease conditions associated with ACAT-2 activity, e.g., in the treatment of gall stones.
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申请公布号 |
US6869937(B1) |
申请公布日期 |
2005.03.22 |
申请号 |
US20000605166 |
申请日期 |
2000.06.27 |
申请人 |
THE REGENTS OF THE UNIVERSTIY OF CALIFORNIA;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS |
发明人 |
CASES SYLVAINE;FARESE, JR. ROBERT V.;ERICKSON SANDRA K.;NOVAK SABINE;ACCAD MICHEL |
分类号 |
C12N9/10;(IPC1-7):A01N43/04;A61K31/70;A61K38/00;C12N9/00;C12N5/00 |
主分类号 |
C12N9/10 |
代理机构 |
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地址 |
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