发明名称 NAPHTYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHOSPHODIESTERASE ISOENZYME 4 (PDE4) INHIBITORS
摘要 The invention relates to compounds of formula I in free or salt form, where R<SUP>1 </SUP>is a monovalent aromatic group having up to 10 carbon atoms, and R<SUP>2 </SUP>is a cycloaliphatic group having up to 8 ring carbon atoms. Compositions containing them, methods for their preparation and their use as pharmaceuticals are also described.
申请公布号 PL368286(A1) 申请公布日期 2005.03.21
申请号 PL20020368286 申请日期 2002.11.04
申请人 NOVARTIS AG 发明人 DENHOLM ALASTAIR;KELLER THOMAS HUGO;MCCARTHY CLIVE;PRESS NEIL JOHN;TAYLOR ROGER JOHN
分类号 A61K31/4375;A61P1/04;A61P1/12;A61P1/16;A61P3/10;A61P3/14;A61P7/00;A61P7/06;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P11/04;A61P17/00;A61P17/12;A61P19/08;A61P19/10;A61P21/02;A61P21/04;A61P25/00;A61P25/16;A61P25/24;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D471/04 主分类号 A61K31/4375
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