发明名称 |
Process for preparing peptidyl heterocyclic ketone derivatives |
摘要 |
The present invention relates to novel processes for the preparation of peptidyl heterocyclic ketones of the general formula (I) wherein all variables are as herein defined. The present invention further relates to novel pharmaceutical salts and processes for their preparation. The peptidyl heterocyclic ketones of formula (I) are potent and selective inhibitors of tryptase, useful for the treatment and prevention of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
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申请公布号 |
US2005059607(A1) |
申请公布日期 |
2005.03.17 |
申请号 |
US20040902755 |
申请日期 |
2004.07.29 |
申请人 |
BRESLAV MICHAEL;HARRIS BRUCE;KENNEY BIRDELLA;MAIER THOMAS;ROESSLER ARMIN;VILLANI FRANK;WEIGL ULRICH;ZHANG-PLASKET FAN;ZHONG HUA |
发明人 |
BRESLAV MICHAEL;HARRIS BRUCE;KENNEY BIRDELLA;MAIER THOMAS;ROESSLER ARMIN;VILLANI FRANK;WEIGL ULRICH;ZHANG-PLASKET FAN;ZHONG HUA |
分类号 |
A61K31/198;A61K38/04;A61K38/05;C07D277/64;C07D417/12;(IPC1-7):A61K38/05 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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