| 发明名称 |
COMPOSITIONS AND METHODS FOR TRANSEPITHELIAL MOLECULAR TRANSPORT |
| 摘要 |
The invention relates to fragments of Clostridium botulinum HC that can be linked with an entity (e.g., an antigen, a particle, or a radionuclide) and used to deliver the entity across a non-keratinized epithelial membrane of an animal. The fragments are useful, for example, for making vaccines, antidotes, and anti-toxins and in situations in which rapid uptake of an agent by an animal is desired.
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| 申请公布号 |
WO03101484(A9) |
申请公布日期 |
2005.03.17 |
| 申请号 |
WO2003US17408 |
申请日期 |
2003.06.02 |
| 申请人 |
THOMAS JEFFERSON UNIVERSITY;SIMPSON, LANCE;MAKSYMOWYCH, ANDREW;PARK, JONG-BEAK |
发明人 |
SIMPSON, LANCE;MAKSYMOWYCH, ANDREW;PARK, JONG-BEAK |
| 分类号 |
A23L1/30;A61K38/00;A61K39/00;A61K39/02;A61K39/07;A61K39/08;A61K39/10;A61K39/106;A61K39/12;A61K39/193;A61K39/215;A61K39/385;A61K39/395;A61K47/42;A61K47/48;A61K49/04;A61K51/00;A61P31/04;A61P31/12;C07K14/33;C12N5/06;C12N5/10;C12N15/09;(IPC1-7):A61K39/08 |
主分类号 |
A23L1/30 |
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