发明名称 |
Human kininogen D3 domain polypeptide as an anti-angiogenic and anti-tumor agent |
摘要 |
Human kininogen domain 3 (HK-D3) polypeptides and biologically active variants and derivatives of HK-D3 are anti-angiogenic. These molecules are used to inhibit angiogenesis or treat a disease or condition in which angiogenesis is pathogenic. Because of their anti-angiogenic potential, these molecules are useful in the treatment of cancer by inhibiting or reversing the growth of primary or metastatic tumors.
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申请公布号 |
US2005058599(A1) |
申请公布日期 |
2005.03.17 |
申请号 |
US20030661784 |
申请日期 |
2003.09.15 |
申请人 |
DONATE FERNANDO;MAZAR ANDREW P. |
发明人 |
DONATE FERNANDO;MAZAR ANDREW P. |
分类号 |
A61K38/00;A61K49/00;C07K14/81;(IPC1-7):A61K51/00;A61K38/17 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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