发明名称 Chemically modified metabolites of regulatory peptides and methods of producing and using same
摘要 The present invention relates to a peptide of Formula I, or a pharmaceutically acceptable salt thereof: X-P Formula I wherein: P is a DPPIV peptide metabolite of regulatory peptides obtained by cleavage of the two N-terminal amino acids; and X is defined by Formula II: wherein: A is selected from the group consisting of C1-C10 alkylene, C2-C10 alkenylene, C2-C10 alkynylene, C1-C10 heteroalkylene, C2-C10 heteroalkenylene, C2-C10 heteroalkynylene and phenyl; and B is selected from the group consisting of aryl, substituted aryl, heteroaryl, substituted heteroaryl and C3-C7 cycloalkyl.
申请公布号 US2005059605(A1) 申请公布日期 2005.03.17
申请号 US20040768974 申请日期 2004.01.30
申请人 PERI KRISHNA;HABI ABDELKRIM;GRAVEL DENIS 发明人 PERI KRISHNA;HABI ABDELKRIM;GRAVEL DENIS
分类号 C07K14/575;C07K14/60;C07K14/605;C12N9/48;(IPC1-7):A61K38/08;C07K7/06 主分类号 C07K14/575
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