摘要 |
Disclosed are compounds of the formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein W, R<1>, R<2>, R<7>, R<8>, R<9>, and R<10> are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds. |
申请人 |
ARRAY BIOPHARMA INC.;WALLACE, ELI, M.;LYSSIKATOS, JOSEPH, P.;MARLOW, ALLISON, L.;HURLEY, BRIAN, T.;KOCH, KEVIN |
发明人 |
WALLACE, ELI, M.;LYSSIKATOS, JOSEPH, P.;MARLOW, ALLISON, L.;HURLEY, BRIAN, T.;KOCH, KEVIN |