发明名称 BENZYL ALCOHOL DERIVATIVES OR SALTS THEREOF
摘要 <p>The invention aims at providing novel low-molecular compounds which have G-CSF-like activities and can substitute for G-CSF preparations. The invention relates to G-CSF-like agonists containing as the active ingredient benzyl alcohol derivatives represented by the general formula (1) or salts thereof: wherein R&lt;1&gt; is hydrogen or the like; A is oxygen or the like; X&lt;1&gt; is hydrogen or the like; Y&lt;1&gt; is optionally substituted phenyl or the like; Z&lt;1&gt; is hydrogen or the like; and n is an integer of 1 to 16, with the proviso that the case wherein R&lt;1&gt; is lower alkyl, X&lt;1&gt; is a halogen atom at the 5-position; Y&lt;1&gt; is imidazolyl; the -A(CH2)n-Z&lt;1&gt; group is present at the 2-position; A is oxygen; and Z&lt;1&gt; is hydrogen or optionally substituted phenyl is excluded.</p>
申请公布号 WO2005023235(A1) 申请公布日期 2005.03.17
申请号 WO2004JP12621 申请日期 2004.09.01
申请人 TANIYAMA, TADAYOSHI;SSP CO., LTD.;KIRIN BEER KABUSHIKI KAISHA;KAIHO, TERUMITSU;KUSANO, KOUJI;USUI, DAISAKU;MOGI, KINICHI 发明人 KAIHO, TERUMITSU;KUSANO, KOUJI;USUI, DAISAKU;MOGI, KINICHI;TANIYAMA, TADAYOSHI
分类号 A61P7/00;A61P37/02;A61P43/00;C07C43/23;C07D233/54;C07D233/60;C07D233/64;C07D521/00;(IPC1-7):A61K31/085;A61K31/403;A61K31/40;A61K31/495;A61K31/537;A61K31/41;A61K31/440;C07D213/30;C07D295/08;C07D257/04;C07D235/08;C07D401/12;C07D327/06;C07D209/48;C07D207/06;A61K31/418;A61K31/417 主分类号 A61P7/00
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