| 发明名称 |
METHOD OF SEARCHING SUBSTANE HAVING ANTIDIABETIC ACTIVITY |
| 摘要 |
<p>The present invention provides a screening method of a substance which inhibits binding of a condensed purine derivative to a pancreatic beta cell or a treated product of the cell, a substance which inhibits binding of a condensed purine derivative to a protein capable of the condensed purine derivative, and a substance which inhibits the expression or enzymatic activity of a protein capable of a condensed purine derivative, which comprises using the condensed purine derivative and a pancreatic beta cell or a treated product of the cell or a protein capable of binding to the condensed purine derivative. <IMAGE></p> |
| 申请公布号 |
EP1514942(A1) |
申请公布日期 |
2005.03.16 |
| 申请号 |
EP20030725810 |
申请日期 |
2003.05.16 |
| 申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
731IGURO, HIROKI;OSHIMA, YUKO;SUGIMOTO, SEIJI;MATSUBARA, MASAHIRO;UENO, KIMIHISA;MORI, KIYOTOSHI;NAKANISHI, SATOSHI;YANO, HIROSHI |
| 分类号 |
C12Q1/04;A61K31/53;A61K31/5377;A61K31/55;A61K45/00;A61P3/10;A61P5/50;A61P43/00;C07D251/70;C07D487/14;C07K14/47;C12N9/02;C12Q1/32;G01N33/50;G01N33/569;G01N33/66;(IPC1-7):C12Q1/04;A61K31/537;C07D403/14;C07D405/14;G01N33/15 |
主分类号 |
C12Q1/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
